Golgi-Cox impregnation has been one of the most effective techniques for studying both the normal and abnormal morphology of neurons as well as glia. Using the Golgi technique, subtle morphological alterations in neuronal dendrites and dendritic spines have been discovered in the brains of animals treated with drugs as well as in the postmortem brains of patients with neurological diseases. However, the reliability and time-consuming process of Golgi staining have been major obstacles to the widespread application of this technique.
NDT104-FD Rapid GolgiStainTM Kit is designed based on the principle of the methods described by Ramon-Moliner (1970), Glaser and Van der Loos (1981). This kit has not only dramatically improved and simplified the Golgi-Cox technique but also proven to be extremely reliable and sensitive for demonstrating morphological details of neurons and glia, especially dendritic spines. The Kit has been tested extensively and widely use on the brains from several species of animals as well as on the specimens of postmortem human brains
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